Recovering from an ill-fated affair with a married man, Gabe finds solace in the relationship he maintains with his ex-wife and daughter. On the other side of town, Ernesto evades life at home with his current live-in ex-boyfriend by spending much of his spare time in the hospital with an ailing past love. Impervious to the monotony of their blue-collar world, they maintain an unwavering yearning for romance. The emotional isolation the two men have grown accustomed to is captured in a subtle, optimistic, poetic fashion while avoiding melodrama.

Jay Pritchett sits at the head of a large and unconventional family. Now in his second marriage to his gorgeous young wife, Gloria, Jay has been given something of a second chance. Still, old habits are hard to break, and it's trial by fire as he tries to adapt to life with the same passion and vigor that Gloria exhibits, which are matched by her precocious 12-year-old son, Manny. There are some culture clashes, a few misunderstandings, but also plenty of sweet victories along the way. Jay's grown daughter, Claire, and her husband, Phil, are the proud parents of three kids with whom they want that open, healthy, honest relationship. It's not always easy, especially when you have Haley, a teenage daughter who's growing up a little fast, Alex, a too-smart-for-her-own-good middle daughter and Luke, a scatterbrained boy. Add to this that Phil is just a big kid himself, even if he does always have the best intentions. Claire is the anchor, trying her best to run a tight ship and determined...

A talented, but distracted photographer, Lola, on the verge of success in both love and work, could lose it all if she doesn't make it to a crucial meeting on time. But, as usual, Lola is late. With her job and girlfriend on the line, she has three chances to make it right. In a desperate race through the streets and back rooms of San Francisco, time grows short-will Lola make it? Will she come at all? With a pop sensibility that mixes live action, animation and still photography, And Then Came Lola explores love's age old question in a fresh new way, "If you try, try again, will you finally get it right?"